DO NOT ATTEMPT TO PLAY THIS WITHOUT A DISK IN YOUR BD, IT WILL CORRUPT YOUR FILES AND YOU MAY HAVE TO REFORMAT YOUR HDD

What I've done:

Followed the instructions that were provided by plamenz, all credit goes to him for he is one of the PS3 Gods that made this possible.

Replaced the missing folder ASSASSIN_ISO in USER DIR
Edited the PARAM.SFO from 3.50 to work on FW 3.41 manually. You do not have to run this in patch mode, it is done for you.

What you have to do:

---->This part is EXTREMELY important. Before you do anything, copy EP0001-BLES00909_00-AC2TITLEUPDATE01-A0101-V0100-PE.pkg to a thumb drive and install it first. It is included in the download folder after you unrar it.

After you have installed the .pkg, you can move the game to your external or internal HDD and then run it as you normally would. Updating the game via PSN is optional. I didn't do it, so I know that it is not necessary. When you first load the game you might get a black screen and it may seem like it's not working, but be patient and wait, it will load. Then the game will do a mandatory install and you will be on your way.

Make sure you have the latest .hex with Hermes V4b with PSN flashed to your board.